Inorganic Synthesis, Coordination and Medicinal Inorganic Chemistry Lab.
PUBLICATIONS
Patent
1. Title: Phosphorus protecting groups and methods of preparation and thereof
Inventors: Douglas J. Dellinger, Luca Monfregola, Marvin H. Caruthers, Mithun Roy,
International Publication Number: WO 2015/168461 A2, Date: November 05, 2015.
Book Chapter
3. Akhil R. Chakravarty and Mithun Roy, “Photoactivated DNA cleavage and anticancer activity of 3d-metal complexes” Progress in Inorganic Chemistry, Ed. K. D. Karlin, Vol. 57, 2011, pp119-202. Journal impact factor (IF): 9.33
2. Dulal Musib, Maynak Pal, Uday Sankar Allam, Mithun Roy*, "Brief history, pathophysiology, transmission of SARS-CoV-2 virus, and recent advances on transition metal complexes and nanocomposites as the potent antiviral agents from COVID-19 perspectives" Nanostructured Biomaterials, 2022,1-48
1. Maynak Pal, Sharmila Wahengbam, Mithun Roy*, " Identification of hypoxia-targeting drugs in the tumor microenvironment and prodrug strategies for targeting tumor hypoxia", 2023, pp 369-401.
Research Articles
Publications from NIT Manipur
2024
30. Rintu Bhowmik, Aarti Upadhyay, Maynak Pal, Arpan Bera, Mithun Roy*, A new iron (III) complex-functionalized selenium nanowires (Fe@SeNWs) for potential phototherapeutic applications with red light, New J. Chem., 48, 5465-5474, 2024.
29. Rintu Bhowmik, Mithun Roy*, Recent advances on the development of NO-releasing molecules (NORMs) for biomedical applications, European J. Med. Chem., 268, 116217, 2024.
28. Sharmila Wahengbam, Dulal Musib, Mithun Roy*, Recent Advances on the Development of Early Transition Metal Complexes for Photo-Assisted Cytotoxicity Applications, Chemistryselect, 9, e202302969, 2024.
27. Maynak Pal, Aarti Upadhyay, Neha Masarkar, Arpan Bera, Sukhes Mukherjee, Mithun Roy*, Folate-assisted targeted photocytotoxicity of red-light-activable iron(III) complex co-functionalized gold nanoconjugates (Fe@FA-AuNPs) against HeLa and triple-negative MDA-MB-231 cancer cells, Dalton Trans., 53, 2108-2119, 2024.
26. Gobinda Bag, Dulal Musib, Md Kausar Raza, Annie Castonguay, Mithun Roy*, Recent advances on the photo-chemotherapeutic potential of manganese carbonyl complexes, Polyhedron, 249, 116778, 2024.
2023
25. Dulal Musib, Moubani Mukherjee, Mithun Roy*, Emerging trends of La(III)-based compounds as the strategic tools for photodynamic therapy, Inorganica Chem. Acta. 558, 121751, 2023.
24. Dulal Musib, Aarti Upadhyay, Maynak Pal, Md Kausar Raza, Indranil Saha, Amit Kunwar, Mithun Roy*, Red light-activable biotinylated copper (II) complex-functionalized gold nanocomposite (Biotin-Cu@AuNP) towards targeted photodynamic therapy, J. Inorg. Biochem., 243, 112183, 2023.
2022
23. Abhishek Panwar, Maynak Pal, Mithun Roy*, Photo-chemical aspects of iron complexes exhibiting photo-activated chemotherapy (PACT), J. Inorg. Biochem.,2022,112055.
22. Arup K Kabi, Maynak Pal, Raghuram Gujjarappa, Chandi C Malakar*, Mithun Roy*, Overview of hydroxychloroquine and remdesivir on severe acute respiratory syndrome coronavirus 2 (Sars-CoV-2), J. Heterocycl. Chem., 2022.
21. SAR-based approach to explore in silico ferrocene analogues as the potential inhibitors of major viral proteins of SARS-CoV-2 virus and human Ca2+- channel blocker, Indian journal of chemistry (IJC), 61(4), 370-384,2022
20. Dulal Musib, Vanitha Ramu, Md Kausar Raza, Aarti Upadhyay, Maynak Pal, Amit Kunwar*, Mithun Roy*, La (iii) - curcumine-functionalized gold nanocomposite as a red light activable mitochondria targeting PDT agent, Inorg. Chem. Front., 2022,9, 686-701.
2021
19. Mrityunjoy Pal, Dulal Musib, Maynak Pal, Gopal Rana, Gobinda Bag, Subrata Dutta and Mithun Roy*, A noncovalent hybrid of [Pd(phen)(OAc)2] and st-DNA for the enantioselective hydroamination of β-nitrostyrene with methoxyamine, Org. Biomol. Chem., 2021, Advance Article
18. Maynak Pal, Vanitha Ramu, Dulal Musib, Amit Kunwar, Arunima Biswas and Mithun Roy*, Iron(III) complex-functionalized gold nanocomposite as a strategic tool for targeted photochemotherapy in red light, Inorg. Chem., 2021, 60, 6283–6297.
17. Bandana Sanasam, Md Kausar Raza, Dulal Musib and Mithun Roy*, Photochemical and photocytotoxic evaluation of new Oxovanadium (IV) complexes in photodynamic application, J. Chem. Sci., 2021, 133, (https://doi.org/10.1007/s12039-021-01896-4)
16. Maynak Pal, Dulal Musib and Mithun Roy*, Transition metal complexes as potential tools against SARS-CoV-2: an in silico approach, New J. Chem., 2021, 45, 1924-1933.
15. Dulal Musib, Md Kausar Raza, Mrityunjoy Pal and Mithun Roy*, A red light-activable MnI(CO)3-functionalized gold nanocomposite as the anticancer prodrug with theranostic potential, Appl. Orgmet. Chem., 2021, 35, e6110.
2020
14. Dulal Musib, Md Kausar Raza, Salam Sujata Devi and Mithun Roy*, A reversible, benzothiazole-based “Turn-on” fluorescence sensor for selective detection of Zn2+ ions in vitro, J. Chem. Sci., 2020, 132
13. Bandana Sanasam, Md K. Raza, Dulal Musib, Maynak Pal, Mrityunjoy Pal, Mithun Roy* Photodynamic Applications of New Imidazo[4,5-f][1,10]phenanthroline Oxidovanadium(IV) Complexes: Synthesis, Photochemical, and Cytotoxic Evaluation, ChemistrySelect, 2020, 5, 13824-13830.
12. Longjam Reena Devi, Md Kausar Raza, Dulal Musib, Mithun Roy* “New selenonapthaquinone-based copper (II) complexes as the next-generation photochemotherapeutic agents” Anticancer Agents in Medicinal Chemistry, 2020, 21, 33-41.
(DOI: 10.2174/1871520620999200727204237)
11. Dulal Musib, Mrityunjoy Pal, Md Kausar Raza and Mithun Roy*, Photo-physical, theoretical and photo-cytotoxic evaluation of a new class of lanthanide(III)–curcumin/diketone complexes for PDT application, Dalton Trans., 2020,49, 10786-10798.
10. Akhil R. Chakravarty* Uttara Basu*, Mithun Roy* “Recent advances in the chemistry of iron-basedchemotherapeutic agents” Coor. Chem. Rev., 2020, 417, 213-339
9. S. Binita Chanu , Md Kausar Raza , Dulal Musib , Mrityunjoy Pal , Maynak Pal and Mithun Roy * Potent Photochemotherapeutic Activity of Iron(III) Complexes on Visible Light-induced Ligand to Metal Charge Transfer, Chemistry Letters, 2020, 49, 724-727.
8. Dulal Musib, L. Reena Devi, Md Kausar Raza, S. Binita Chanu and Mithun Roy*, A New Thiophene-based Aggregation-induced Emission Chemosensor for Selective Detection of Zn2+ Ions and Its Turn Off, Chemistry Letters, 2020, 49, 473-476. (https://doi.org/10.1246/cl.200001).
7. L. Reena Devi, Md. Kausar Raza, Dulal Musib, Joshila Devi and Mithun Roy*, Nucleus targeting anthraquinone-based copper (II) complexes as the potent PDT agents: Synthesis, photo-physical and theoretical evaluation, Inorg. Chim. Acta, 2020, 500, 119208.
2019
6. D. Musib, Md Kausar Raza, Martina Kh., Mithun Roy*, Mn(I)-based photoCORMs for trackable, visible light-induced CO release and photocytotoxicity to cancer cells, Polyhedron, 2019, 172,125-131.(https://doi.org/10.1016/j.poly.2019.04.008).
5. S. Binita Chanu, Md. Kausar Raza, Samya Banerjee, Pooja Meena, Dulal Musib and Mithun Roy* ROS dependent antitumour activity of photo-activated iron(III) complexes of amino acids, J. Chem. Sci., 2019, 131: 9.
2018
4. Dulal Musib, Md. Kausar Raza, Somashree Kundu and Mithun Roy*, Modulating in vitro photodynamic activity of copper(II) complexes, Eur. J. Inorg. Chem., 2018, 2018, 2011-2018.
3. Dulal Musib, Samya Banerjee, Aditya Garai, Uzeeta Soraisam and Mithun Roy*, Synthesis, theory and in vitro photo-dynamic activities of new copper(II)-histidinito complexes, ChemistrySelect, 2018, 3, 2767-2775.
2017
2. S. Binita Chanu, Samya Banerjee, Mithun Roy* Potent anticancer activity of photo-activated oxo-bridged diiron(III) complexes, Eur. J. Med. Chem., 2017, 125, 816-824.
1. Subhadeep Roy, Sibasish Paul, Mithun Roy, Rajen Kundu, Luca Monfregola and Marvin H. Caruthers* Pyridinium Boranephosphonate Modified DNA Oligonucleotides, J. Org. Chem., 2017, 82, 1420–1427
Other Publications
1. Tridib K. Goswami, Sudarshan Gadadhar, Mithun Roy, Munirathinam Nethaji, Anjali A. Karande, Akhil R. Chakravarty, “Ferrocene-conjugated copper(II) complexes of L-methionine and phenanthroline bases: synthesis, structure, and photocytotoxicActivity” Organometallics, 2012, 31, 3010-3021 (IF: 4.25).
2. Mithun Roy, Shanta Dhar, Basudev Maity and Akhil R. Chakravarty “Dicopper(II) complexes showing DNA hydrolase activity and monomeric adduct formation with bis(4-nitrophenyl)phosphate” Inorg. Chim. Acta, 2011, 375, 173-180 (IF: 2.041).
3. Tridib K. Goswami, B. V. S. K. Chakravarthi, Mithun Roy, Anjali A. Karande and Akhil R. Chakravarty, “Ferrocene-conjugated L-tryptophan copper(II) complexes of phenanthroline bases showing DNA photocleavage activity and cytotoxicity” Inorg. Chem., 2011,50, 8452-8464 (IF: 4.794).
4. Mithun Roy, B. V. S. K. Chakravarthi, C. Jayabaskaran, Anjali A. Karande and Akhil R. Chakravarty, “Impact of metal binding on the antitumor activity and cellular imaging of a metal chelator cationic imidazopyridine derivative” Dalton Trans., 2011, 40, 4855-4864 (IF: 4.10).
5. Basudev Maity, B. V. S. K. Chakravarthi, Mithun Roy, Anjali A. Karande and Akhil R. Chakravarthi, “DNA photocleavage and cytotoxic properties of ferrocene-conjugates” Eur. J. Inorg. Chem, 2010, 9, 1379-1386 (IF: 2.965).
6. Basudev Maity, Mithun Roy and Akhil R. Chakravarty, “Photoactivated DNA cleavage by ferrocene-appended terpyridyl copper(II) complexes of phenanthroline Bases”, Organometallics, 2010, 29, 3632–3641 (IF: 4.253).
7. Mithun Roy, Tuhin Bhowmick, Ramkumar Santhanagopal, Suryanaryana Ramakurar and Akhil R. Chakravarty, “Photo-induced double-strand DNA and site-specific protein cleavage activity of L-histidine (µ-oxo)diiron(III) complexes of heterocyclic bases”, Dalton Trans., 2009, 4671–4682 (IF: 4.10).
8. Mithun Roy, Ramkumar Santhanagopal and Akhil R. Chakravarty, “DNA binding and oxidative DNA cleavage activity of (µ-oxo)diiron(III) complexes in visible light”, Dalton Trans., 2009, 1024-1033 (IF: 4.10).
9. Tridib K. Goswami, Mithun Roy, Munirathinam Nethaji, and Akhil R. Chakravarty, “Photo-induced DNA and protein cleavage activity of ferrocene-appended L-methionine reduced Schiff base copper(II) complexes of phenanthroline bases”, Organometallics, 2009, 28, 1992-1994 (IF: 4.253).
10. Sounik Saha, Ritankar Majumdar, Mithun Roy, Rajan R. Dighe and Akhil R. Chakravarty, “An iron complex of dipyridophenazine as a potent photocytotoxic agent in visible light”, Inorg. Chem., 2009, 48, 2652-2663 (IF: 4.794).
11. Ramakrishna Rao, Mithun Roy, Ashis K. Patra and P. R. Chetana, “New ternary copper(II) complexes of L-alanine and heterocyclic bases: DNA binding and oxidative DNA cleavage activity” Inorg. Chim. Acta., 2009, 362, 4692–4698 (IF: 2.041).
12. Basudev Maity, Mithun Roy, Sounik Saha and Akhil R. Chakravarty, “Photo-induced DNA and protein cleavage activity of ferrocene-conjugated ternary copper(II) complexes of heterocyclic bases”, Organometallics, 2009, 28, 1495-1505 (IF: 4.253).
13. Mithun Roy, Tuhin Bhowmick, Suryanarayanarao Ramakumar, Munirathinam Nethaji, and Akhil R. Chakravarty, “Double-strand DNA cleavage from photodecarboxylation of (µ-oxo)diiron(III) L-histidine complex in visible light”, Dalton Trans., 2008, 3542-3545 (IF: 4.10).
14. Basudev Maity, Mithun Roy, Akhil. R. Chakravarty, “Ferrocene-conjugated copper(II) dipyridophenazine complex as a multifunctional model nuclease showing DNA cleavage in red light” J. Org. Met. Chem., 2008, 693, 1395-1399 (IF: 2.302).
15. Mithun Roy, Biswarup Pathak, Ashis K. Patra, E. D. Jemmis, M. Nethaji and Akhil R. Chakravarty, “New insights into the visible light-induced DNA cleavage activity of dipyridoquinoxaline complexes of bivalent 3d-metal ions”, Inorg. Chem., 2007, 46, 11122-11132 (IF: 4.794).
16. Mithun Roy, Sounik Saha, Ashis K. Patra, Munirathinam Nethaji and Akhil R. Chakravarty “Ternary iron(III) complex showing photocleavage of DNA in the PDT window”, Inorg. Chem., 2007, 46, 4368-4370 (IF: 4.794).
17. Mithun Roy, Ashis K. Patra, Arindam Mukherjee, Munirathinam Nethaji and Akhil R. Chakravarty “Ternary iron(II) complexes of phenanthroline bases showing DNA binding and cleavage activity”, Indian J. Chem. Sec. A, 2007, 46A, 227-237 (IF: 0.628).